{"id":10631,"date":"2021-09-15T17:09:02","date_gmt":"2021-09-15T15:09:02","guid":{"rendered":"https:\/\/team-mastery.eu\/opentox-virtual-conference-2021-team-mastery-partecipa-allincontro-globale\/"},"modified":"2025-04-17T11:35:36","modified_gmt":"2025-04-17T09:35:36","slug":"opentox-virtual-conference-2021-team-mastery-partecipa-allincontro-globale","status":"publish","type":"post","link":"https:\/\/team-mastery.eu\/it\/opentox-virtual-conference-2021-team-mastery-partecipa-allincontro-globale\/","title":{"rendered":"OpenTox Virtual Conference 2021: TEAM mastery partecipa all\u2019incontro globale"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<\/p>\n<h3><strong>OpenTox Virtual Conference 2021:<\/strong> TEAM mastery partecipa all\u2019incontro globale<\/h3>\n<h2>TEAM mastery S.r.l. parteciper\u00e0 all&#8217;OpenTox Virtual Conference 2021, un incontro globale virtuale di quattro giorni per un mondo pi\u00f9 sicuro. L&#8217;evento si svolger\u00e0 online 20-24 settembre.<\/h2>\n<p>Il 22 settembre, alle 15.25, la nostra collega Costanza Rovida terr\u00e0 una presentazione sulle <strong>Challenges in implementing NAMs (New Approach Methodologies) for Endocrine Disruption characterization of chemicals in the regulatory context<\/strong>.<\/p>\n<p>Le New Approach Methodologies (NAMs) in tossicologia rappresentano un cambio di paradigma rispetto al sistema tradizionale. Le NAM comprendono un nuovo e pi\u00f9 efficiente sistema basato su metodi senza animali che vengono combinati per comprendere i possibili effetti sulla salute di una sostanza chimica. Questo approccio richiede competenza per decidere il miglior metodo da applicare e per interpretarne i risultati.<\/p>\n<p>L&#8217;attivit\u00e0 ED \u00e8 specie-specifica e ha bisogno di un approccio focalizzato sull&#8217;uomo e basato sullo studio del meccanismo d&#8217;azione. L&#8217;approccio tramite studi su animali ha molte limitazioni, dovute alle differenze di specie- e ai problemi derivati dalla dose-risposta non monotonica, ma anche al disegno del protocollo. Il rischio di risultati falso-negativi \u00e8 alto, ma anche i risultati falso-positivi possono rappresentare un problema con sostanze che vengono escluse dal mercato senza motivo.<\/p>\n<p>L&#8217;applicazione dei NAM in questo settore potrebbe risolvere molti problemi, ma la loro applicazione \u00e8 ancora limitata soprattutto perch\u00e9 non c&#8217;\u00e8 un incentivo per la loro applicazione. I regolamenti UE sono poco aperti a nuovi approcci e i test sugli animali sono spesso obbligatori. L&#8217;approccio in vitro \u00e8 suggerito su base volontaria e solo per chiarire un meccanismo.<\/p>\n<p><strong>When<\/strong>: 20-24 September 2021<\/p>\n<p><strong>Website<\/strong><em>:\u00a0<a href=\"https:\/\/www.opentox.net\/events\/virtual-conference-2021\">https:\/\/www.opentox.net\/events\/virtual-conference-2021<\/a><\/em>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>TEAM mastery parteciper\u00e0 all&#8217;OpenTox Virtual Conference 2021, un incontro globale virtuale di quattro giorni per un mondo pi\u00f9 sicuro. L&#8217;evento si svolger\u00e0 online 20-24 settembre.<\/p>\n","protected":false},"author":1,"featured_media":9524,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[212],"tags":[],"class_list":["post-10631","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-eventi-passati-it"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>OpenTox Virtual Conference 2021 - TEAM mastery<\/title>\n<meta name=\"description\" content=\"TEAM mastery parteciper\u00e0 all&#039;OpenTox Virtual Conference 2021, un incontro globale virtuale di quattro giorni per un mondo pi\u00f9 sicuro. 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